Date: Mon, December 10, 15:00- Place: Room Dw601, D Block, IIS, The University of Tokyo Invited Speaker: Prof. James A. Simmons (Brown University) Title: Bat sonar as a computational process in neuroscience Abstract: In FM echolocation of big brown bats (Eptesicus fuscus), the minimum "object" in perception is a point-reflector (a single glint) at a specific target range. The echo has a spectrum identical to the broadcast (~20-100 kHz), and the bat's image of the target's distance is based on echo delay. Two or more glints comprise a typical real object. While the image of the target's distance is based on echo delay, the image also represents the distances to the glints. This part of the image is based on the interference spectrum for closely spaced delay separations. The bat's delay accuracy is 10-15 nanoseconds, and the limit for delay resolution is about 2 microseconds. Nevertheless, big brown bats perceive targets in terms of the actual distances to the individual glints, even for separations of only a few microseconds. Often, more than one object is present, so that the content of an auditory scene in echolocation consists of the distances to the various objects, including the distances to their individual glints. Neurons in the bats ascending auditory pathway register the timing of reflections by single spikes at stable latencies, with a precision of ~10-40 microseconds or less in the brainstem and ~300 microseconds in the midbrain and cortex. The sharpness of delay-tuning for cortical neurons is much less precise than spike latency. Delay-tuning as a feature is ~50% of the best delay for each cell, which is ~1-10 milliseconds at different best delays. In contrast, spike latency variability is only about 300 microseconds. Because the sharpness of delay-tuned neurons is too coarse to account for perception of closely-spaced delays, and because different subpopulations of delay-tuned neurons respond to different glint interference patterns, even though the bat perceives all interference patterns as corresponding delays, the origin of the bat's perception of targets cannot simply be which population coding from which neurons are active and which neurons are inactive. Instead, perception of each "object" must be based on the timing of spikes circulating in recurrent neuronal circuits between the midbrain and cortex. Neuronal responses reveal such reverberatory signaling. An auditory model is presented that postulates how these timing signals are generated and how they explain what the bat perceives.